picksbycard
August 23, 2026No. 113
Arc B580 · 12GB GDDR6

Can the Arc B580 run Mistral NeMo 12B Instruct (2407)?

Fits comfortably at Q4_K_M.

Mistral NeMo 12B Instruct (2407) is 12.2B parameters. At Q4_K_M the weights are about 6.8 GiB; with the 1.5 GiB runtime reserve that is 8.3 GiB against the card's 12GB, leaving about 3.7 GiB for context.

All three quants

12GB card
QuantWeightsWith reserveVerdictHeadroom
Q4_K_Mthe everyday quant6.8 GiB8.3 GiBFits comfortably3.7 GiB
Q8_0near-lossless12.0 GiB13.5 GiBOnly with CPU offloadshort 1.5 GiB
FP16full weights22.7 GiB24.2 GiBDoes not fitshort 12.2 GiB

Verdict rules: fits comfortably when weights plus reserve sit within 85% of VRAM; tight when they fit with little left for context; CPU offload when they exceed VRAM by up to 2x (runs, slowly, with layers in system RAM); no beyond that. The KV cache per token depends on the model's architecture and is not modelled here.

Good match. Get the card.

The Arc B580 clears Mistral NeMo 12B Instruct (2407) at Q4_K_M. Live listings below; this page was rebuilt 2026-08-23.

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About the model

Mistral NeMo 12B Instruct (2407) by Mistral AI: 131,072-token native context, text, released 2024 under the Apache-2.0. Model card → · Hosted pricing on PicksByModel →

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